They aren’t produced according the their genes. They don’t affect DNA like viruses do. They are a removed lower energy configuration of a protein. When the removed protein bumps into a healthy form of itself, the forces between the molecules pull the healthy protein into the prion shape. Then they go their separate ways, exponentially eating holes through tissues.
The protein targeted by CWD is different in cervids, it has like an extra loop that is important for its function. So if a CWD prion bumps into the human version of the protein, nothing happens. But, if some weird interaction allowed it to actually work, it’s feasible a human prion could be created.
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