Nothing serious. In GNOME my alternate chars and compose were set to the same key after the upgrade; just had to change one. There was an issue with “sloppy” window focus, but they fixed that upstream before the official release of 45. I upgraded during the beta.
Agreed on Hetzner, although I have used customer support—to add another distro option. Sent them a web link, and they had it uploaded under my account by the next day.